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Isoflavone


The conversion of the isoflavone glucoside conjugates and the isoflavone glucosides to the aglucone isoflavones can be effected in the substrate from which the isoflavones are to be extracted prior to the extraction, or may be effected in the isoflavone enriched extract after separation of the extract from the insoluble materials.
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Samples. "In addition, every month between interviews, the girls will fill out a short questionnaire and keep a journal of their menstrual cycles once they begin, " she said. The researchers will perform full analyses of the collected data in the coming months, but HornRoss was able to divulge some of their preliminary results. "Based on just the first 160 girls enrolled and adjusting for all the pertinent factors, such as body composition, we have seen no effect between isoflavone level and earlier onset of menarche, " she reported. She and her research group have, however, found that girls who have a body type that is proportioned with larger hips and smaller waist rather than the opposite have earlier menarche, and also confirmed long-established reports linking greater height and increased body fat with an earlier first period. In addition, she said, "Although we are not seeing an association between soy consumption and breast development, we are seeing that less isoflavone exposure is associated with delayed public hair growth during pubertal development." She cautioned that these results are based on less than 70 percent of the girls recruited for the study, and that these preliminary findings may not pan out as the girls who joined the study later are different in terms of soy consumption and ethnicity than the girls joining earlier. She hopes to report the cross-sectional results of her full study in the coming months. The more powerful longitudinal analyses will be available after the end of the two-year follow-up period.

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To the colon and faeces Gorbach et al. 1967, Justesen et al. 1984, Marteau et al. 2001 ; . Oropharyngeal microbes have been reported to dominate in jejunal biopsies of humans Sullivan et al. 2003 ; , whereas E. coli and streptococci were the most common findings in the jejunum of 35 mongrel dogs Thompson et al. 1998 ; . Higher or comparable counts of fungi, staphylococci and lactobacilli have been reported in the human ileum than faeces Gorbach et al. 1967 ; . Similarly we found staphylococci, yeasts and also other catalase-producing cocci and non-fermentative gram-negative facultative rods more frequently in the canine jejunum than in faeces but less lactobacilli. Additionally, some species isolated from jejunal samples were undetected in faeces. Marteau et al. 2001 ; reported facultative bacteria to be as numerous as anaerobes in the human caecum. This seems to be true in the jejunum as well, as shown in the present stydy. B. fragilis proved to be the most frequent species of the B. fragilis group in the canine small intestine but not in faeces. In agreement with our observation, B. fragilis has been reported to be the most frequent isolate from mucosal surfaces of humans but not in colon contents Namavar et al. 1989 ; . In the present study the canine jejunal microbiota was also found to be less stable than the faecal microbiota. The canine duodenal microbiota monitored by DGGE profiles has been shown to differ more between individual dogs than between samples from the same dog Suchodolski et al. 2004 ; . The canine fecal bacterial DGGE profiles have individually unique and stable characteristic banding patterns Simpson et al. 2002. Source: british medical journal, 2003; 3 3-316 hrt: a difficult decision august 8, 2003 ; ivanhoe newswire ; women taking hormone replacement therapy may want to talk to their doctors about whether to stay on the drugs, for example, soy isoflavones prostate.
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9Dangers of Dietary Isoflavones at levels above those found in traditional diets The Risks Of Abandoning "The Precautionary Principle" by Soy Online Service . : soyonlineservice.co.nz "Soy - Abundance Of Health Hazards" . : mayanmajix soy01.

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Ucsf the isoflavone clover extract trial ice ; a three-center, randomized controlled trial testing the effect of two dietary supplements containing phytoestrogens derived from red clover on hot flashes and quality of life for menopausal women and isoniazid. References: Parts of page 1 are from an earlier draft version. Up-date at . : westonaprice soy dangersisoflavones ; 1. Nutrition during Pregnancy and Lactation. California Department of Health, 1975. 2. Fukutake M, Takahashi M, Ishida K, Kawamura H, Sugimura T, Wakabayashi K. Quantification of genistein and genistin in soybeans and soybean products. Food Chem Toxicol 1996; 34: 457-461. Nagata C, Takatsuka N, Kurisu Y, Shimizu H. Decreased serum total cholesterol concentration is associated with high intake of soy products in Japanese men and women. J Nutr 1998 Feb; 128 2 ; : 209-13. 4. Nakamura Y, Tsuji S, Tonogai Y. Determination of the levels of isoflavonoids in soybeans and soy-derived foods and estimation of isoflavonoids in the Japanese daily intake. J AOAC Int 2000; 83: 635-650. This exhaustive study of Chinese diets found that legume consumption ranged from 0 to 58 grams per day, with a average of 13 grams According to the researchers, about 2 3's of this was supplied by soy beans, giving average consumption of about 9 grams of soy products per day. Chen J, Campbell TC, Li J, Peto R. Diet, Lifestyle and Mortality in China. A study of the characteristics of 65 counties. Monograph, joint publication of Oxford University Press, Cornell University Press, China People's Medical Publishing House, 1990. Isoflavne content is estimated be about 3 mg per day based on an average amount of 30 mg total isoflavones per 100 grams of tofu. USDA-Iowa State University Database on the Isoflagone Content of Foods 1999. 6. Y Ishizuki, et al, "The effects on the thyroid gland of soybeans administered experimentally in healthy subjects, " Nippon Naibunpi Gakkai Zasshi 1991, 767: 622-629 Cassidy A, Bingham S, Setchell KD. Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women. J Clin Nutr 1994; 60 3 ; : 333-340. 8. Washington Post Health Section, January 30, 2001. 9. Burros M. Doubts Cloud Rosy News on Soy. New York Times, January 26, 2000.
Armenia HiT By: Tatul Hakobyan, Mihran Nazaretyan, Tatyana Makarova, Movses Aristakesyan, Hovhannes Margaryants and Ellen Nolte Edited by: Ellen Nolte and Erica Richardson Available at : euro.who.int Document E89732 Since independence, the health care system in Armenia has undergone numerous changes that have effectively transformed a centrally run state system into a fragmented health care system that is largely financed from out-of-pocket payments. Armenia is increasingly reforming the health system from one that emphasises the treatment of disease and responds to epidemics to one which emphasises prevention, family care and community participation and vasodilan, because isoflavone intake.
Manufacturer Not quoted accepted Merit Organics Ltd Parkin Laboratories Avron Laboratories Not quoted accepted Caldern Pharmaceuticals Ltd H. L. Pharmaceuticals Kansas Laboratories Pvt Ltd Greenco Biologicals [P] Ltd Standard Pharmaceuticals Ltd Diamond Drugs & Chemical Works Centurion Laboratories Deleted item Greenco Biologicals [P] Ltd Eskaar Pharmaceuticals Stadmed Private Limited Zephyr Pharmaceutical Pvt Ltd Centurion Laboratories Emma Drugs & Chemicals Stadmed Private Limited Stadmed Private Limited Drakt Pharmaceutical Pvt Ltd Aurobindo Pharma Ltd Stadmed Private Limited Arvind Remedies Ltd Medifair [Product of Ralph Health Care] Kansas Laboratories Pvt Ltd Centurion Laboratories Dey's Drugs & Chemicals [Product of Elite Pharma] Not quoted accepted Centurion Laboratories C. I. Laboratories Aurobindo Pharma Ltd Concept Pharmaceuticals Ltd Standard Pharmaceuticals Cotec Pharma C. I. Laboratories Medifair [Product of Zydus Cadila] Zephyr Pharmaceutical Pvt Ltd Finop Drugs [P] Ltd Centurion Laboratories 14. Table 2. Response of all 10 patients on cladribine therapy and ketorolac.

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Utian WH, Boggs PP. The North American Menopause Society 1998 Menopause Survey. Part I: Postmenopausal women's perceptions about menopause and midlife. Menopause 1999; 6 2 ; : 122-128. Consensus Opinions: Achieving long-term continuance of menopausal ERT HRT. Menopause 1998; 5 2 ; : 69-76. Clinical challenges of perimenopause. Menopause 2000; 7 1 ; : 5-13. Effects of menopause and estrogen replacement therapy or hormone replacement therapy in women with diabetes mellitus. Menopause 2000; 7 2 ; in press ; . A decision tree for the use of estrogen replacement therapy or hormone replacement therapy in postmenopausal women. Menopause 2000; 7 2 ; in press ; . The role of isoflavones in menopausal health. Menopause 2000; 7 3 ; in press ; . * O'Connor AM, Tugwell P, Wells GA, et al. A decision aid for women considering hormone therapy after menopause: decision support framework and evaluation. Patient Educ Couns 1998; 33 3 ; : 267-279. * O'Connor AM, Rostom A, Fiset V, et al. Decision aids for patients facing health treatment or screening decisions: systematic review. BMJ 1999; 319 7212 ; : 731-734. * O'Connor AM, Drake, ER, Fiset V, et al. The Ottawa patient decision aids. Eff Clin Pract 1999; 2 4 ; : 163-170. * O'Connor AM, Tugwell P, Wells GA, et al. Randomized trial of a portable self-administered decision aid for post-menopausal women considering long-term preventive hormone therapy. Med Decis Making 1998; 18 3 ; : 295-303. Physical Activity and Health: A Report of the Surgeon General.1996. Available from cdc.gov nccdphp sgr sgr . Retrieved 1 11 00. Rannevik G, Jeppsson S, Johnell O, et al. A longitudinal study of the perimenopausal transition: altered profiles of steroid and pituitary hormones, SHBG and bone mineral density. Maturitas 1995; 21 2 ; : 103-113. * Roter DL, Stewart M, Putnam, SM, et al. Communication patterns of primary care physicians. JAMA 1997; 277 4 ; : 350-356. Roter DL, Hall JA, Kern DE, et al. Improving physicians' interviewing skills and reducing patients' emotional distress: a randomized clinical trial. Arch Intern Med 1995; 155 17 ; : 18771884. * Rothert ML, Holmes-Rovner M, Rovner D, et al. An educational intervention as decision support for menopausal women. Res Nurs Health 1997; 20 5 ; : 377-387. * Rothert M, Padonu G, Holmes-Rovner M, et al. Menopausal women as decision makers in health care. Exp Gerontol 1994; 29 3-4 ; : 463-468. Santoro N, Brown JR, Adel T, et al. Characterization of reproductive hormonal dynamics in the perimenopause. J Clin Endocrinol Metab 1996; 81 4 ; : 1495-1501. Sherwin BB. Sex hormones and psychological functioning in postmenopausal women. Exp Gerontol 1994; 29 3-4 ; : 423-430. Smith RN, Holland EF, Studd JW. The symptomatology of progestogen intolerance. Maturitas 1994; 18 2 ; : 87-91. Society of Obstetricians and Gynaecologists of Canada. Policy statement 73. Hormone replacement therapy: an update. The benefits of hormone replacement therapy and counseling issues related to breast cancer. Toronto, Ontario: Ribosome Communications, Inc., 1998. * Strull WM, Lo B, Charles G. Do patients want to participate in medical decision making? JAMA 1984; 252 21 ; : 2990-2994.

LDL oxidation by phyto-oestrogens and ascorbic acid. Free Radical Biology and Medicine 2000; 29: 79-89. Kurzer MS, Xu X. Dietary phytoestrogens. Annual Review of Nutrition 1997; 17: 35381. Setchell K, Lydeking-Olsen E. Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies. American Journal of Clinical Nutrition 2003; 78: 593S609S. Simonet WS, Lacey DL, Dunstan CR. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997; 89: 309319. Scambia G, Mango D, Signorile PG. Clinical effects of a standardized soy extract in postmenopausal women: a pilot study. Menopause 2000; 7: 10511. Huntley AL, Ernst E. Soy for the treatment of perimenopausal symptoms -- a systematic review. Maturitas 2004; 47: 19 Upmalis DH, Lobo R, Bradley L. Vasomotor symptom relief by soy isoflavone extract tablets in postmenopausal women: a multicenter, double-blind, randomized, placebocontrolled study. Menopause 2000; 7: 23642. Krebs EE, Ensrud KE, MacDonald R. Phytoestrogens for treatment of menopausal symptoms: a systematic review. Obstetrics and Gynecology 2004; 104: 82436. St. Germain A, Peterson CT, Robinson JG. Isoflavone-rich or isoflavone-poor soy protein does not reduce menopausal symptoms during 24 weeks of treatment. Menopause 2001; 8: 1726. This P, De La Rochefordiere A, Clough K. Phytoestrogens after breast cancer. Endocrine Related Cancer 2001; 8: 12934. Han KK, Soares JM, Haidar MA. Benefits of soy isoflavone therapeutic regimen on menopausal symptoms. Obstetrics and Gynecology 2002; 99: 38494. Van Patten CL, Olivotto IA, Chambers GK. Effects of Soy Phytoestrogens on hot flushes in postmenopausal women with breast cancer: a randomized, controlled clinical trial. Journal of Clinical Oncology 2002; 20: 144955. Cooper CW, Aihie A. Osteoporosis: recent advances in pathogenesis and treatment. Quarterly Journal of Medicine 1994; 87: 2039. Anderson JJ, Garner SC. Phytoestrogens and bone. Baillieres Clinical Endocrinology and Metabolism 1998; 12: 54357. Alekel DL, Germain AS, Peterson CT. Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women. American Journal of Clinical Nutrition 2000; 72: 84452. Atkinson C, Compston JE, Day NE. The effects of phytoestrogen isoflavones on bone density in women: a double-blind, randomized, placebo-controlled trial. American Journal of Clinical Nutrition 2004; 79: 32633. Heaney RP. The bone-remodeling transient: implications for the interpretation of clinical studies of bone mass change. Journal of Bone and Mineral Research 1994; 9: 151523. Potter SM, Baum JA, Teng H. Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women. American Journal of Clinical Nutrition 1998; 68: 1375S9S. Uesugi T, Fukai Y, Yamori Y. Beneficial effects of soybean isoflavone supplementation on bone metabolism and serum lipids in postmenopausal Japanese women: a fourweek study. Journal of the American College of Nutrition 2002; 21: 97102. Dalais FS, Ebeling PR, Kotsopoulos D. The effects of soy protein containing isoflavones on lipids and indices of bone resorption in postmenopausal women. Clinical Endocrinology 2003; 58: 7049. Gallagher JC, Satpathy R, Rafferty K. The effect of soy protein isolate on bone metabolism. Menopause 2004; 11: 2908. Erdman JW, Stillman RJ, Boileau RA. Provocative relation between soy and bone maintenance. American Journal of Clinical Nutrition 2000; 72: 67980. Recker R, Lappe J, Davies K. Characterization of perimenopausal bone loss: a prospective study. Journal of Bone and Mineral Research 2000; 15: 196573 and ketotifen. Strated [154]. The 24-h distribution of the blood pressure effect of antihypertensive drugs can also be quantified by applying specific mathematical indices to the analysis of ABPM recordings, such as the trough-topeak ratio and the smoothness index [155157].

Table 5. Classification and sources of phytoestrogens. The precursors and biologically active components are also indicated Coumestans Isoflavones Lignans Leguminous plants soybean, lentils, Flaxseeds, grains, cereals, fruits Bean sprouts, fodder crops beans, clover ; guava ; , berries lingonberry, bramble ; , vegetables broccoli ; Coumesterol Matairesinol Biochanin A Enterolactone Genistein p-ethylphenol Formononetin Daidzein Equol, O-demethylangolensin O-Dma ; Secoisolariciresinol Enterodiol and lamictal.
Regardless of whether an individual's stress was caused by interpersonal or environmental factors, frequent low mood rates were virtually identical for people who used social exercise, recreation, talking with friends and family ; versus solitary alcohol, smoking, eating, being alone ; coping Brain Wired Differently in Bipolar strategies frequent low mood rates: Disorder 11.8% v. 11.3%, respectively ; . People CHICAGO, IL -- American Journal of who said smoking was their primary This study, conducted by McNeill Psychiatry; October 2000 -- In a new coping strategy had a low mood rate of Lehman, Inc. on behalf of BASF, finding that appears to solidify the 15%. People using prayer meditation to assessed respondents' mood based on biological-genetic roots of bipolar the CES-D screening tool, developed by battle the blues had low mood rates of disorder, researchers at the University of the Center for Epidemiologic Studies of only 6.6%. Michigan Health System reported that the National Institutes of Mental Health, Herbal Stimulant May Be Deadly patients with the disorder have about with depression equating to CES-D one third more monoamine-releasing USA -- Associated Press; November 7, cells in their brains than patients who do scores greater than or equal to 15 and 2000 -- Ephedra, an herbal stimulant "frequent low mood" to CES-D scores not have the illness. used by millions of Americans for between 10 and 14. bodybuilding and weight loss, can cause In a study of patients with the more "This frequent low mood group -- 10% heart attacks, stroke, seizures, and death severe type 1 bipolar disorder of those surveyed -- find their quality of in otherwise healthy young people, researchers used positron emission life is quite stressful on a regular basis, " researchers say. At least 54 deaths and tomography PET ; scans to track a about 1, 000 reports of complications said Michael Seidman, MD, "People radioactive tracer that binds only to a with frequent low mood are not using all have been linked to ephedra since the protein that is contained in cells that mid-1990s. In a study commissioned by the methods for coping available to release monoamines dopamine, them." Signs of frequent low mood can the FDA, researchers concluded that the serotonin, and norepinephrine. They include difficulty sleeping or excessive dietary supplement, also known as ma found that monoamine binding sites in huang, poses a risk that far outweighs sleep, poor appetite, fatigue, lessened the patients were 31% greater in the any benefits it might have. ability to focus on important things, a thalamus and 28% greater in the ventral persistent state of having "the blues, " Researchers noted that most of the cases brain stem than in healthy controls. In and unexplained weight loss. they studied involved healthy young addition, the researchers conducted people. Some had been taking ephedra Nearly half the people interviewed functional tests with the same patients that showed higher levels of monoamine reported that "relationships" and "other for just days or weeks, and two women who became pregnant while taking it cells were associated with lower scores people's behavior" had the greatest lost their babies. Hundreds of ephedra on tests of executive function and verbal negative impact on their moods 45% products are on the market and often and 44% respectively ; . One-third also learning. sold in health food stores under various cited "financial concerns" 33% ; and "To put it simply, these patients' brains brand names. "work" 31% ; . Eighteen percent of are wired differently, " said lead women say that PMS strongly influences Publications of Interest & researcher Jon-Kar Zubieta, MD, PhD, their moods. Overall, women had higher Importance. assistant professor of psychiatry and rates of low mood than men 13.3% radiology. Journal of Maintenance in the versus 10% ; . Frequent low mood was Frequent Low Mood Afflicts 1 in Addictions also more likely in 18-24 year olds 10 Persons After a long delay, another edition 18.6% ; , in members of unmarried NEW YORK, NY -- PRNewswire; couples 17.1% ; , and in the unemployed 2000, Vol 1, No 4, 114 pp ; of this fine publication edited by J. Thomas Payte, November 1, 2000 -- A depression 18% ; . "The data from the present study suggest that stress increases vulnerability to cocaine addiction. Further, these results are consistent with reports that early life stress is common among drug addicts, " the authors write, for instance, foods containing isoflavones.

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Table V. Plasma Cholesterol Level in Female Hamsters Fed Casein- or ISP-Based Diets with or without Soy Isoflavones1, 2 and lamotrigine. It is preferred to extract the isoflavones useful in the compositions and methods of the present invention from the plant materials in which they naturally occur. Take a look at the billions and billions of dollars the drug industry spends on promotion and compare that to what they spend on research and development and levothyroxine!
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Establishment of the Subsidiary Maping and Splitting the Internal Processes Definition of the Part of the Business Lean DSO Structure approx. 200 people ; Contribution value acknowledged in the amount equal to local valuer valuation and lithobid.
Relative amount of isodlavone after reaction 10 min with D. nigrescens -glucosidase supernatant 0 0 0 1710 467 1118 pellet 0 0 0 383 488 670 min control supernatant 90 109 88 pellet 92 103 93.

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Hodgkin Building, Guy's Campus, SE1 1UL, London, UK. -- Adult male hooded Lister rats were either fed a diet containing 150 microg g soya phytoestrogens or a soya-free diet for 18 days. This concentration of phytoestrogens should have been sufficient to occupy the oestrogen-beta, but not the oestrogen-alpha, receptors. -- Using in situ hybridisation, significant reductions were found in brain-derived neurotrophic factor BDNF ; mRNA expression in the CA3 and CA4 region of the hippocampus and in the cerebral cortex in the rats fed the diet containing phytoestrogens, compared with those on the soya-free diet. -- No changes in glutamic acid decarboxylase-67 or glial fibrillary acidic protein mRNA were found. This suggests a role for oestrogen-beta receptors in regulating BDNF mRNA expression 58 - 58 Dangers of Dietary Isoflavones at levels above those found in traditional diets The Risks Of Abandoning "The Precautionary Principle" by Soy Online Service . : soyonlineservice.co.nz "Soy - Abundance Of Health Hazards" . : mayanmajix soy01 and lithium and isoflavone.
Methoxy 7 isoflavone
The product is filtered, thoroughly dried and, after addition of 5 g powdered copper, heated to 25 degre on completion of the evolution of gas, the residue is crystallized frommethanol, yielding 5 g of 7-isopropyloxy-isoflavone, 11 degree.

The method defined in claim 2 wherein said compound is 7-isopropoxyisoflavone and loxitane. Nature's Plus Source of Life Woman 60 Tabletten nur fr Frauen Die Multivitamin und Mineralstoffformel mit Vollwertkonzentraten, Calcium, Folat & Lutein und FemEffektKomplex nur fr Frauen. Source of Life Women versorgt SIE mit einer synergistischen Kombination aus Vitaminen, Mineralstoffen, Fett und Aminosuren, Bioflavonoiden und sekundren Pflanzenstoffen fr den garantierten Energieschub. Zustzlich wurden bei dieser Formel noch Isoflavone, eine erhhte Menge Kalzium und ein standardisierter Kruterkomplex hinzugefgt. Vegetarisch. Empfohlene tgliche Verzehrmenge: 2 Tabletten.

Isoflavone phytoestrogens
Omitted from virtually all of these studies, however, is any consideration of the herbal alternatives, regardless of their potential. Soybean isoflav9ne can cure and restrain some cancers related to hormone, such as prostate cancer, galactophore cancer etc 2 ; lowering cholesterol concentration in human body, preventing and curing cardiovascular disease.

Pharmaceutical. [0006] [SOLUTION OF THE INVENTION] Then the present inventors advanced study on the effect and food processing technology from the viewpoint of the effective usage of a soybean hypocotyl. As a result, the present inventors completed this invention finding that heat processed soybean hypocotyl is not only effective for liver cancer, also has the excellent flavour as foodstuffs. [0007] Summary That is, the summary of this invention is the anti-liver cancer foodstuffs and the anti-liver cancer agent which are heat processed soybean hypocotyl as an active ingredient. Hereafter, experiment facts which inventors have reached this invention are described. [0008] 1 ; Soybean hypocotyl The soybean hypocotyl used with this invention may is sufficient as long as it does not almost contain seed coats and it does not lose active ingredients, such as an isoflavone. In order to prepare without containing of seed coats and loss of isoflavone etc., it is suitable to use the hypocotyls separated from the soybean under dry heat. As the preferable method of preparing such a hypocotyl material, the method described in the Japanese Patent Publication No. 04-48417 can be illustrated. [0009] About the obtained soybean hypocotyl by the above an isoflavone content is maintained to 80 % or more. And the free amount of isoflavones is made into 5 % or more, preferably 10 % or more and more preferably 20 % or more. Moreover, the material which is processed with heating to the specific degree which removes a trypsin inhibitory activity substantially is used as a base. In particular the roast process has the excellent property on the processing capacity and the secondary operation using this invention materials. [0010] Incidentally, the method describing in unexamined Japanese patent 08-107749 can be illustrated about the roast method. That is, any device may be used as long as it can dry-heat the sample to 100 degrees C or more. Gas roasters made in Fuji Royal Co., Ltd. etc. ; , electrically heated roasters made in Nippon Glass company etc. ; , hot air roasters made!


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