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Gravity - fluid Spironolactone Aldactoone ; Department Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Clinical Pathology Departmental Section Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Biochemistry Referred Out by Sunnybrook To. 18. Bolognese I, Neskovic AN, Parodi G, et al. Left ventricular remodeling after primary coronary angioplasty: patterns of left ventricular dilation and long-term prognostic implications. Circulation 2002; 106 18 ; : 2351-7. 19. Drazner MH. The transition from hypertrophy to failure: how certain are we? Circulation 2005; 112 7 ; : 936-8. 20. De Marco T, Chatterjee K, Rouleau J-L, Parmley WW. Abnormal coronary hemodynamics and myocardial energetics in patients with chronic heart failure caused by ischemic heart disease and dilated cardiomyopathy. Heart J 1988; 115: 809-15. VMAC Investigators: Intravenous nesiritide vs. nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial. JAMA 2002; 287: 1531-40. Solomon SD, Skali H, Nagesh S, et al. Changes in ventricular size and function in patients treated with valsartan, captopril or both after myocardial infarction. Circulation 2005; 111: 3411-9 Garg R, Yusuf S. For the collaborative group on ACE inhibitor trials. Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. JAMA 1995; 273: 1450-6. Pfeffer MA, Swedberg K, Granger CB, et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: The CHARM overall programme. Lancet 2003; 362: 759-66. Granger CB, McMurray JV, Yusuf S, et al. Effects of candesartan in patients with chronic heart failure and reduced left ventricular systolic function intolerant to angiotensin-converting enzyme inhibitors: The CHARM alternative trial. Lancet 2003; 362: 772-6. McMurray JV, stergren J, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-convertingenzyme inhibitors: The CHARM-Added Trial. Lancet 2003; 362: 767-71. Packer M, Fowler MB, Rocker EB, et al. Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival Copernicus Study ; . Circulation 2002; 106: 2194-9. MERIT-HF Investigators. Effect of metoprolol CR XL in chronic heart failure: Metoprolol CR XL Randomised Intervention Trial in Congestive Heart Failure MERIT-CF ; . Lancet 1999; 353: 2001-7. Pitt B, Zanand F, Remme WJ, et al. For the randomized aldactone evaluation study investigators. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med 1999; 341: 709-17. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. The SOLVD Investigators. N Engl J Med 1992; 327: 685-91. Pfeffer MA, Braunwald E, Moye LA, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 1992; 327 10 ; : 669-77. 32. Sharpe N, Murphy J, Smith H, Hanan S. Preventive treatment of asymptomatic left ventricular dysfunction following myocardial infarction. Eur Heart J 1990; 11 Suppl B: 147-56. 33. Kober L, Torp-Pedersen C, Carlsen JE, et al. A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. Trandolapril Cardiac Evaluation TRACE ; Study Group. N Engl J Med 1995; 333 25 ; : 1670-6. 34. Taylor AL, Ziesche S, Yancy C, et al. Combination of isosorbide dinitrate and hydralazine in Blacks with heart failure. N Engl J Med 2004; 351: 2049-57. Yusuf S, Pfeffer MA, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: The CHARM Preserved Trial. Lancet 2003; 362 9386 ; : 777-81 36. Fukuta H, Sane DC, Brucks S, Little WC. Statin therapy may be associated with lower mortality in patients with diastolic heart failure. A preliminary report. Circulation 2005; 112: 357-63. Zile MR. Treating diastolic heart failure with statins: "phat" chance for pleiotropic benefits. Circulation 2005; 112: 300-3. Mozaffarian D, Nye R, Levy WC. Statin therapy is associated with lower mortality among patients with severe heart failure. J Cardiol 2004; 93: 1124-9. HOW ESSENTIAL IS THE "TRUTH" IN SOCIAL MARKETING CAMPAIGNS? AN ANALYSIS OF THE CURRENT MASS MEDIA ANTI DRUGS CAMPAIGN Lodge M A Mass media campaigns have been a central feature of Australian Government responses to drug issues since the inception of the National Campaign Against Drug Abuse NCADA ; in 1985. Drug education theory and social marketing principles were initially used to guide many of the campaigns. Fear tactics were the wrong tactics and older style films like "Reefer Madness" were scoffed at as ineffective and counter productive. The principles of social marketing were drawn upon to develop sophisticated approaches to dealing with drug related harms that spoke about the real lives of real people. Michael will argue that the current campaign material has gone back to the dark ages, where the approach was to scare people from using drugs. These scare tactics are based on questionable facts about the impact of drug use and exhibit a disdain for the lived experience of Australians who choose to use drugs illicitly. Michael will analyse the campaign material in light of sound drug education theory and modern principles of social marketing. He will outline a scenario that suggests these campaigns will impact negatively on rates of HIV AIDS and hepatitis C among Australians who use drugs illicitly and aldara.
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